Job Description
Role Description
Through internal efforts and collaborations, direct efforts to validate new epigenetic targets in cancer using a variety of approaches, as well as contribute to advance drug discovery efforts directed towards epigenetic enzymes.
Responsibilities
Organizational Relationships:
- Reports into Head of Tumor Cell Biology. Interacts with Medicinal Chemistry group and scientists across Oncology Research Unit (ORU) organization.
Resources Managed:
- Direct supervision of lab leaders and scientists in the Epigenetics group
- Management of external collaborations
Primary Duties:
- Lead a team of scientists dedicated to Chromatin biology, Target Validation and Drug Discovery using in vitro, in vivo, and omics methodologies, in collaboration with partner lines
- Participate in nomination of new potential targets from literature; collaborates with IBB to fully validate targets originating in that group
- Direct genetic and pharmacologic strategies to validate epigenetic targets
- Direct biology efforts in support of epigenetic drug discovery programs
- Identify, develop, and manage external collaborations with world class experts to advance our competitive advantage in improved target validation and drug discovery
- Partner with collaborators and computational biologists, to integrate data and further enhance understanding of target biology
- Ensure scientific rigor across team and focus resources towards TCB and company goals
- Contribute to building a culture that embraces continuous learning and improvement, increasing technical skill base and disease biology expertise; take a proactive role in personal growth and scientific development
- Ability to manage scientists
- Mentor staff scientists and postdoctoral fellows
Qualifications
Training & Education:
- PhD or MD/PhD plus post-doctoral training in Cell Biology, Molecular Biology, Biochemistry (or a comparable biological science) with a cancer-related focus
- Deep and broad knowledge of targets and pathways of importance to cancer biology
- Established expert in epigenetics
- Expert in advanced in vitro and in vivo models; good understanding of relevant methodologies ( eg ChIP/Seq, etc)
- Thorough knowledge of the entire drug discovery process, with good understanding of drug development
Prior Experience:
- At least 12 years experience working primarily on cancer biology and epigenetics
- At least 8 years of experience in industry or academic lab focused on target validation and drug discovery
- Demonstrated ability to identify, develop, and manage successful external collaborations
- Able to work in a team environment; excellent communication skills
- Effective manager of scientific teams
- Demonstrated success in designing and implementing strategy
- Track record of innovation - designing and delivering novel solutions to challenging problems.
Equal Employment Opportunity
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.
Desired Skills & Experience
- PhD or MD/PhD plus post-doctoral training in Cell Biology, Molecular Biology, Biochemistry (or a comparable biological science) with a cancer-related focus
- Deep and broad knowledge of targets and pathways of importance to cancer biology
- Established expert in epigenetics
- Expert in advanced in vitro and in vivo models; good understanding of relevant methodologies ( eg ChIP/Seq, etc)
- Thorough knowledge of the entire drug discovery process, with good understanding of drug development
Prior Experience:
- At least 12 years experience working primarily on cancer biology and epigenetics
- At least 8 years of experience in industry or academic lab focused on target validation and drug discovery
- Demonstrated ability to identify, develop, and manage successful external collaborations
- Able to work in a team environment; excellent communication skills
- Effective manager of scientific teams
- Demonstrated success in designing and implementing strategy
- Track record of innovation - designing and delivering novel solutions to challenging problems.
Apply Now - Resume or CV with Job Post Title
Email: jobs@aarenconsultants.in
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